Showing posts with label Health. Show all posts
Showing posts with label Health. Show all posts

Clinton discharged from hospital, doctors expect full recovery






WASHINGTON (Reuters) – Secretary of State Hillary Clinton was discharged from a New York hospital on Wednesday after being treated for a blood clot near her brain and her doctors expect her to make a full recovery, the State Department said.


Clinton, who has not been seen in public since December 7, was at New York-Presbyterian Hospital under treatment for a blood clot behind her right ear that stemmed from a concussion she suffered in mid-December, the department said on Sunday.






The concussion was the result of an earlier illness, described by the State Department as a stomach virus she had picked up during a trip to Europe that led to dehydration and a fainting spell after she returned to the United States.


Secretary Clinton was discharged from the hospital this evening. Her medical team advised her that she is making good progress on all fronts, and they are confident she will make a full recovery,” Philippe Reines, a deputy assistant secretary of state, said in a statement.


Reines said Clinton was “eager to get back to the office.”


Earlier, State Department spokeswoman Victoria Nuland told reporters at her daily briefing Clinton had been talking with her staff by telephone and receiving memos.


Clinton also spoke to two foreign officials – the U.N. envoy on Syria and the prime minister of Qatar – on Saturday, the day before the State Department disclosed the blood clot and her stay at the hospital.


In a statement released by the State Department on Monday, Clinton’s doctors said she was being treated with blood thinners and would be released from the hospital once the correct dosage had been determined.


(Reporting by Arshad Mohammed; Editing by Sandra Maler and Todd Eastham)


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Gambian leader says to build herbal AIDS-cure hospital






BANJUL (Reuters) – AIDS patients would be offered an herbal cure at a 1,111-bed hospital in Gambia that the president said on Tuesday he plans to build despite medical concerns the treatment is dangerous.


President Yahya Jammeh said in 2007 he had found a remedy of boiled herbs to cure AIDS, stirring anger among Western medical experts who claimed he was giving false hope to the sick.






“With this project coming to fruition, we intend to treat 10,000 HIV/AIDS patients every six months through natural medicine,” Jammeh said in his New Year’s address, adding that he expected the 1,111-bed hospital to open in 2015.


The World Health Organisation and the United Nations have said Jammeh’s HIV/AIDS treatment is alarming mainly because patients are required to cease their anti-retroviral drugs, making them more prone to infection.


Jammeh said in October that 68 HIV/AIDS patients undergoing his herbal remedy had been cured and discharged, the seventh batch since the treatments began five years ago.


Other African leaders have drawn criticism for extolling the power of natural remedies to combat AIDS.


The administration of former South African President Thabo Mbeki was ridiculed for denying there was a link between HIV and AIDS while prescribing meaningless treatments such as beet root instead of internationally proven medicines.


The HIV rate in Gambia is relatively low compared to other African states, with 2 percent of the country’s roughly 1.8 million people infected, according to the United Nations.


Jammeh came to power in Gambia, a sliver of land on Africa’s west coast that is popular with sun-seeking European tourists, in a bloodless military coup in 1994.


He is accused by activists of human rights abuses during his rule, and most recently drew international criticism for executing nine death-row inmates by firing squad.


(Reporting by Pap Saine; Writing by Richard Valdmanis; Editing by Michael Roddy)


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Clinton’s blood clot an uncommon complication






The kind of blood clot in the skull that doctors say Hillary Rodham Clinton has is relatively uncommon but can occur after an injury like the fall and concussion the secretary of state was diagnosed with earlier this month.


Doctors said Monday that an MRI scan revealed a clot in a vein in the space between the brain and the skull behind Clinton’s right ear.






The clot did not lead to a stroke or neurological damage and is being treated with blood thinners, and she will be released once the proper dose is worked out, her doctors said in a statement.


Clinton has been at New York-Presbyterian Hospital since Sunday, when the clot was diagnosed during what the doctors called a routine follow-up exam. At the time, her spokesman would not say where the clot was located, leading to speculation it was another leg clot like the one she suffered behind her right knee in 1998.


Clinton had been diagnosed with a concussion Dec. 13 after a fall in her home that was blamed on a stomach virus that left her weak and dehydrated.


The type of clot she developed, a sinus venous thrombosis, “certainly isn’t the most common thing to happen after a concussion” and is one of the few types of blood clots in the skull or head that are treated with blood thinners, said neurologist Dr. Larry Goldstein. He is director of Duke University‘s stroke center and has no role in Clinton’s care or personal knowledge of it.


The area where Clinton’s clot developed is “a drainage channel, the equivalent of a big vein inside the skull — it’s how the blood gets back to the heart,” Goldstein explained.


It should have no long-term consequences if her doctors are saying she has suffered no neurological damage from it, he said.


Dr. Joseph Broderick, chairman of neurology at the University of Cincinnati College of Medicine, also called Clinton’s problem “relatively uncommon” after a concussion.


He and Goldstein said the problem often is overdiagnosed. They said scans often show these large “draining pipes” on either side of the head are different sizes, which can mean blood has pooled or can be merely an anatomical difference.


“I’m sure she’s got the best doctors in the world looking at her,” and if they are saying she has no neurological damage, “I would think it would be a pretty optimistic long-term outcome,” Broderick said.


A review article in the New England Journal of Medicine in 2005 describes the condition, which more often occurs in newborns or young people but can occur after a head injury. With modern treatment, more than 80 percent have a good neurologic outcome, the report says.


In the statement, Clinton’s doctors said she “is making excellent progress and we are confident she will make a full recovery. She is in good spirits, engaging with her doctors, her family, and her staff.”


___


Online:


Medical journal: http://dura.stanford.edu/Articles/Stam_NEJM05.pdf


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FDA approves Bristol Myers, Pfizer’s anti-clotting drug Eliquis






(Reuters) – U.S. health regulators approved clot prevention drug Eliquis, developed by Bristol Myers-Squibb Co and Pfizer Inc, for treatment in patients with atrial fibrillation, or irregular heartbeats.


The drug, also known as apixaban, was approved by European health regulators last month.






Eliquis belongs to a new class of medicines designed to replace decades-old warfarin for preventing blood clots in heart patients, or after a hip- or knee-replacement surgery.


Eliquis would compete against approved blood clot preventers such as Xarelto from Johnson & Johnson and Bayer, and Pradaxa from Boehringer Ingelheim.


Treating atrial fibrillation, which greatly raises the risk of strokes, is considered by far the largest and most important use for these new drugs.


The oral tablet Eliquis, like Xarelto, works by inhibiting a protein called Factor Xa that plays a critical role in blood clotting. Pradaxa has a slightly different mechanism of action.


However, Eliquis should not be taken by patients with prosthetic heart valves or those with atrial fibrillation caused by a heart valve problem, the U.S. Food and Drug Administration said in a statement.


About 5.8 million people in the United States suffer from atrial fibrillation, the most common form of heart arrhythmia, or irregular heartbeat.


Bristol-Myers shares were up 2 percent at $ 32.48 and Pfizer shares were up 10 cents at $ 24.99 in extended trading.


(Reporting by Prateek Kumar; Editing by Sreejiraj Eluvangal)


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Celebrity bad science: Dried placenta pills and oxygen shots






LONDON (Reuters) – Pop guru Simon Cowell carries pocket-sized inhalable oxygen shots, America’s “Mad Men” actress January Jones favors dried placenta pills, and British soap star Patsy Palmer rubs coffee granules into her skin.


Celebrities rarely shy away from public peddling of dubious ideas about health and science, and 2012 was no exception.






In its annual list of the year’s worst abuses against science, the Sense About Science (SAS) campaign also named former U.S. presidential candidate Mitt Romney for spreading misinformation about windows on planes, and Olympic swimmer Michael Phelps for false justifications for peeing in the pool.


To help set the record straight, SAS, a charity dedicated to helping people make sense of science and evidence, invited qualified scientists to respond to some of the wilder pseudo-scientific claims put about by the rich and famous.


It suggested Romney, who wondered aloud in September why aircraft crews don’t just open the windows when there’s a fire on board, should listen to aeronautical engineer Jakob Whitfield:


“Unfortunately, Mitt, opening a window at height wouldn’t do much good,” the scientist said. “In fact, if you could open a window whilst in flight, the air would rush out…because air moves from the high pressure cabin to the lower pressure outside, probably causing further injury and damage.”


January Jones’s dried placenta pills, which the actress admitted in March she consumed after giving birth, win no favor with Catherine Collins, principal dietician at St George’s Hospital in London.


“Nutritionally, there’s nothing to be gained from eating your placenta – raw, cooked, or dried,” Collins said. “Apart from iron, which can be easily found in other dietary choices or supplements, your placenta will provide toxins and other unsavory substances it had successfully prevented from reaching your baby in utero.”


Gary Moss, a pharmaceutical scientist, patiently points out to Palmer that while caffeine may have an effect on cellulite, rubbing coffee granules into the skin is unlikely to work, since the caffeine can’t escape the granules to penetrate the skin.


Phelps’s claim that it’s fine to pee in the pool because “chlorine kills it” is put straight by biochemist Stuart Jones, who reminds him that “urine is essentially sterile so there isn’t actually anything to kill in the first place”.


And for Cowell, Kay Mitchell a scientist at the Centre for Altitude Space and Extreme Environment Medicine warns that very high levels of oxygen can in fact be toxic – particularly in the lungs, where oxygen levels are highest.


“Celebrity comments travel far and fast, so it’s important that they talk sense,” said Sense About Science’s managing director Tracey Brown. “The implausible and frankly dangerous claims about how to avoid cancer, improve skin or lose weight are becoming ever more ridiculous. And unfortunately they have a much higher profile than the research and evidence.”


To encourage more vigilance among celebrity pseudo-scientists in the future, SAS provided a checklist of “misleading science claims” it suggests should be avoided:


* “Immune boosting” – you can’t and you don’t need to


* “Detox” – your liver does this


* “Superfood” – there is no such thing, just foods that are high in some nutrients


* “Oxygenating” – your lungs do this


* “Cleansing” – you shouldn’t be trying to cleanse anything other than your skin or hair.


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Justice Sotomayor refuses to block contraceptives mandate






(Reuters) – U.S. Supreme Court Justice Sonia Sotomayor has refused to block enforcement starting next week of a requirement in President Barack Obama‘s 2010 healthcare overhaul that some companies provide insurance coverage for contraceptive drugs and devices.


In an order issued on Wednesday, Sotomayor said two for-profit companies controlled by Oklahoma City billionaire David Green and his family did not qualify for an injunction while they challenge the requirement in court.






Hobby Lobby Stores Inc, an arts and crafts chain with more than 500 stores, and Mardel Inc, a chain of 35 Christian-themed bookstores, said it violated their religious beliefs to require that their group health plans cover treatments that could induce abortions.


They said they face possible fines of $ 1.3 million a day if they disobey the mandate, which takes effect on January 1.


Sotomayor, who hears emergency appeals from the 10th Circuit, said it was not “indisputably clear” that Hobby Lobby and Mardel deserved an injunction, noting that lower courts have been divided in similar cases on whether temporary relief is proper.


“Even without an injunction pending appeal, the applicants may continue their challenge to the regulations in the lower courts,” and following a final judgment ask the Supreme Court at that time to consider their appeal, she said.


Sotomayor did not rule on the merits of the companies’ religious-based claims.


Kyle Duncan, general counsel for the nonprofit Becket Fund for Religious Liberty, which represents the chains, did not immediately respond to requests for comment. At least 42 lawsuits have been filed over the issue, the fund has said.


Hobby Lobby and Mardel claimed that the contraceptives provision violated the First Amendment to the U.S. Constitution, as well as the Religious Freedom Restoration Act of 1993.


But on November 19, Oklahoma federal judge Joe Heaton refused to issue a preliminary injunction, saying the chains did not have the same religious rights as Green family members. Then on Thursday, the 10th U.S. Circuit Court of Appeals in Denver refused to issue a injunction during the chains’ appeal.


Forbes magazine in September called David Green, 71, the 79th richest American, with a net worth of $ 4.5 billion.


The case is Hobby Lobby Stores Inc et al v. Sebelius et al, U.S. Supreme Court, No. 12A644.


(Reporting by Jonathan Stempel in New York; Editing by Cynthia Osterman)


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Obesity declining in young, poorer kids: study






NEW YORK (Reuters Health) – The number of low-income preschoolers who qualify as obese or “extremely obese” has dropped over the last decade, new data from the Centers for Disease Control and Prevention show.


Although the decline was only “modest” and may not apply to all children, researchers said it was still encouraging.






“It’s extremely important to make sure we’re monitoring obesity in this low-income group,” said the CDC‘s Heidi Blanck, who worked on the study.


Those kids are known to be at higher risk of obesity than their well-off peers, in part because access to healthy food is often limited in poorer neighborhoods.


The new results can’t prove what’s behind the progress, Blanck told Reuters Health – but two possible contributors are higher rates of breastfeeding and rising awareness of the importance of physical activity even for very young kids.


Blanck and her colleagues used data on routine clinic visits for about half of all U.S. kids eligible for federal nutrition programs – including 27.5 million children between age two and four.


They found 13 percent of those preschoolers were obese in 1998. That grew to just above 15 percent in 2003, but dropped slightly below 15 percent in 2010, the most recent study year included.


Similarly, the prevalence of extreme obesity increased from nearly 1.8 percent in 1998 to 2.2 percent in 2003, then dropped back to just below 2.1 percent in 2010, the research team reported Tuesday in the Journal of the American Medical Association.


Whether kids are obese is determined by their body mass index (BMI) – a measure of weight in relation to height – and by their age and sex.


For example, a four-year-old girl who is 40 inches tall would be obese if she was 42 pounds or heavier. A two-year-old boy who is 35 inches tall qualifies as obese at 34 pounds or above, according to the CDC’s child BMI calculator. (The CDC’s BMI calculator for children and teens is available here:.)


The new findings are the first national data to show obesity and extreme obesity may be declining in young children, Blanck said.


“This is very encouraging considering the recent effort made in the field including by several U.S. federal agencies to combat the childhood obesity epidemic,” said Dr. Youfa Wang, head of the Johns Hopkins Global Center on Childhood Obesity in Baltimore.


Blanck said between 2003 and 2010 researchers also saw an increase in breastfeeding of low-income infants. Breastfeeding has been tied to a healthier weight in early childhood.


Additionally, states and communities have started working with child care centers to make sure kids have time to run around and that healthy foods are on the lunch menu, she added.


Parents can encourage better eating by having fruits and vegetables available at snack time and allowing their young kids to help with meal preparation, Blanck said.


Her other recommendations include making sure preschoolers get at least one hour of activity every day and keeping television sets out of the bedroom.


“The prevalence of overweight and obesity in many countries including in the U.S. is still very high,” Wang, who wasn’t involved in the new study, told Reuters Health in an email.


“The recent level off should not be taken as a reason to reduce the effort to fight the obesity epidemic.”


SOURCE: http://bit.ly/JjFzqx Journal of the American Medical Association, online December, 25, 2012.


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Allergies, extra weight tied to bullying






NEW YORK (Reuters Health) – Kids who have food allergies or are overweight may be especially likely to get bullied by their peers, two new studies suggest.


Not surprisingly, researchers also found targets of bullying were more distressed and anxious and had a worse quality of life, in general, than those who weren’t picked on.






Bullying has become a concern among parents, doctors and school administrators since research and news stories emerged linking bullying – including online “cyberbullying” – with depression and even suicide.


“There has been a shift and people are more and more recognizing that bullying has real consequences, it’s not just something to be making jokes about,” said Dr. Mark Schuster, chief of general pediatrics at Boston Children’s Hospital and a professor at Harvard Medical School, who wrote a commentary published with the new research.


Studies suggest between one in ten and one in three of all kids and teens are bullied – but those figures may vary by location and demographics, researchers noted.


The new findings come from two studies published Monday in the journal Pediatrics.


In one, Dr. Eyal Shemesh from the Mount Sinai Medical Center in New York and his colleagues surveyed 251 kids who were seen at an allergy clinic and their parents. The children were all between age eight and 17 with a diagnosed food allergy.


Just over 45 percent of them said they’d been bullied or harassed for any reason, and 32 percent reported being bullied because of their allergy in particular.


“Our finding is entirely consistently with what you find with children with a disability,” Shemesh told Reuters Health.


A food allergy, he said, “is a vulnerability that can be very easily exploited, so of course it will be exploited.”


The kids in the study were mostly white and well-off, the researcher said – a group that you’d expect would be targeted less often. So bullying may be more common in poorer and minority children who also have food allergies.


But allergies aren’t the only cause of teasing and harassment by peers.


In another study, researchers from Yale University in New Haven, Connecticut, found that almost two-thirds of 361 teens enrolled in weight-loss camps had been bullied due to their size.


That likelihood increased with weight, so that the heaviest kids had almost a 100 percent chance of being bullied, Rebecca Puhl and her colleagues found. Verbal teasing was the most common form of bullying, but more than half of bullied kids reported getting taunted online or through texts and emails as well.


‘START THE CONVERSATION’


Shemesh’s team found only about half of parents knew when their food-allergic child was being bullied, and kids tended to be better off when their families were aware of the problem.


He said parents should feel comfortable asking kids if they’re being bothered at school or elsewhere – and that even if it only happens once, bullying shouldn’t be ignored.


“We want parents to know,” he said. “Start the conversation.”


“Parents whose kids have a food allergy should really be aware that their kids have the kind of characteristic that often leads to being bullied,” Schuster told Reuters Health. “They should be working with the school to handle the food allergy in a way that isn’t going to make it more likely that their kids will be bullied – and they need to be attuned to their kids.”


That’s the same for parents of overweight and obese children, he added.


“Kids need their parents to be their allies in these situations,” he said. “Their parents can help them still feel strong.”


SOURCE: http://bit.ly/cxXOG Pediatrics, online December 24, 2012.


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Few tests done at toxic sites after superstorm






OLD BRIDGE, N.J. (AP) — For more than a month, the U.S. Environmental Protection Agency has said that the recent superstorm didn’t cause significant problems at any of the 247 Superfund toxic waste sites it’s monitoring in New York and New Jersey.


But in many cases, no actual tests of soil or water are being conducted, just visual inspections.






The EPA conducted a handful of tests right after the storm, but couldn’t provide details or locations of any recent testing when asked last week. New Jersey officials point out that federally designated Superfund sites are EPA’s responsibility.


The 1980 Superfund law gave EPA the power to order cleanups of abandoned, spilled and illegally dumped hazardous wastes that threaten human health or the environment. The sites can involve long-term or short-term cleanups.


Jeff Tittel, executive director of the Sierra Club in New Jersey, says officials haven’t done enough to ensure there is no contamination from Superfund sites. He’s worried toxins could leach into groundwater and the ocean.


“It’s really serious and I think the EPA and the state of New Jersey have not done due diligence to make sure these sites have not created problems,” Tittel said.


The EPA said last month that none of the Superfund sites it monitors in New York or New Jersey sustained significant damage, but that it has done follow-up sampling at the Gowanus Canal site in Brooklyn, the Newtown Creek site on the border of Queens and Brooklyn, and the Raritan Bay Slag site, all of which flooded during the storm.


But last week, EPA spokeswoman Stacy Kika didn’t respond to questions about whether any soil or water tests have been done at the other 243 Superfund sites. The agency hasn’t said exactly how many of the sites flooded.


“Currently, we do not believe that any sites were impacted in ways that would pose a threat to nearby communities,” EPA said in a statement.


Politicians have been asking similar questions, too. On Nov. 29, U.S. Sen. Frank Lautenberg, D-N.J., wrote to the EPA to ask for “an additional assessment” of Sandy’s impact on Superfund sites in the state.


Elevated levels of lead, antimony, arsenic and copper have been found at the Raritan Bay Slag site, a Superfund site since 2009. Blast furnaces dumped lead at the site in the late 1960s and early 1970s, and lead slag was also used there to construct a seawall and jetty.


The EPA found lead levels as high as 142,000 parts per million were found at Raritan Bay in 2007. Natural soil levels for lead range from 50 to 400 parts per million.


The EPA took four samples from the site after Superstorm Sandy: two from a fenced-off beach area and two from a nearby public playground. One of the beach samples tested above the recreational limit for lead. In early November, the EPA said it was taking additional samples “to get a more detailed picture of how the material might have shifted” and will “take appropriate steps to prevent public exposure” at the site, according to a bulletin posted on its website. But six weeks later, the agency couldn’t provide more details of what has been found.


The Newtown Creek site, with pesticides, metals, PCBs and volatile organic compounds, and the Gowanus Canal site, heavily contaminated with PCBs, heavy metals, volatile organics and coal tar wastes, were added to the Superfund list in 2010.


Some say the lead at the Raritan Bay site can disperse easily.


Gabriel Fillippeli, director of the Center for Urban Health at Indiana University-Purdue University Indianapolis, said lead tends to stay in the soil once it is deposited but can be moved around by stormwaters or winds. Arsenic, which has been found in the surface water at the site, can leach into the water table, Fillippeli said.


“My concern is twofold. One is, a storm like that surely moved some of that material physically to other places, I would think,” Fillippeli said. “If they don’t cap that or seal it or clean it up, arsenic will continue to make its way slowly into groundwater and lead will be distributed around the neighborhood.”


The lack of testing has left some residents with lingering worries.


The Raritan Bay Slag site sits on the beach overlooking a placid harbor with a view of Staten Island. On a recent foggy morning, workers were hauling out debris, and some nearby residents wondered whether the superstorm increased or spread the amount of pollution at the site.


“I think it brought a lot of crud in from what’s out there,” said Elise Pelletier, whose small bungalow sits on a hill overlooking the Raritan Bay Slag site. “You don’t know what came in from the water.” Her street did not flood because it is up high, but she worries about a park below where people go fishing and walk their dogs. She would like to see more testing done.


Thomas Burke, an associate dean at the Johns Hopkins School of Public Health, says both federal and state officials generally have a good handle on the major Superfund sites, which often use caps and walls to contain pollution.


“They are designed to hold up,” Burke said of such structures, but added that “you always have to be concerned that an unusual event can spread things around in the environment.” Burke noted that the storm brought in a “tremendous amount” of water, raising the possibility that groundwater plumes could have changed.


“There really have to be evaluations” of communities near the Superfund sites, he said. “It’s important to take a look.”


Officials in both New York and New Jersey note they’ve also been monitoring less toxic sites known as brownfields and haven’t found major problems. The New York DEC said in a statement that brownfields in that state “were not significantly impacted” and that they don’t plan further tests for storm impacts.


Larry Ragonese, a spokesman for the New Jersey Department of Environmental Protection, said the agency has done visual inspections of major brownfield sites and also alerted towns and cities to be on the lookout for problems. Ragonese said they just aren’t getting calls voicing such concerns.


Back at the Raritan Bay slag site, some residents want more information. And they want the toxic soil, which has sat here for years, out.


Pat Churchill, who was walking her dog in the park along the water, said she’s still worried.


“There are unanswered questions. You can’t tell me this is all contained. It has to move around,” Churchill said.


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Judge orders end to HIV prison segregation in Alabama






BIRMINGHAM, Alabama (Reuters) – A U.S. federal judge ruled on Friday to end the segregation of prisoners with HIV in Alabama, agreeing that it violates the Americans with Disabilities Act (ADA).


“It is evident that, while the … segregation policy has been an unnecessary tool for preventing the transmission of HIV, it has been an effective one for humiliating and isolating prisoners living with the disease,” U. S. District Judge Myron Thompson wrote in his ruling.






South Carolina now remains the only state segregating HIV inmates from the general population. Mississippi ceased a similar practice in March 2010.


The ruling came in response to a lawsuit by the American Civil Liberties Union (ACLU) over what the group contended was a discriminatory practice that prevented most HIV-positive inmates from participating in rehabilitation and retraining programs, including mental health and substance abuse programs, important for their success after prison.


“We won on all counts. It is a total victory and a glorious day for everyone with HIV,” said Margaret Winter, associate director of the ACLU National Prison Project and lead counsel for the plaintiffs.


Proponents of ending the policy sited an out-dated view of HIV/AIDS, which has become increasingly controllable. In the case of a virus transmitted by behavior, and not environment, preventing its spread is easier through proper medical treatment, rather than radical segregation of HIV positive inmates, according to Nancy Mahon, who chairs the Presidential Advisory Council on HIV/AIDS (PACHA).


“We now have ability to suppress the virus and reduce the possibility of transmission to four percent. Alabama and South Carolina have been in the dark ages about this public health sorrow,” said Mahon, who also directs the MAC AIDS Fund, which is financing the ACLU challenges in both states.


“The last thing we want to do is send them back into the community without treatment,” she added.


Two of Alabama’s 29 prisons have dormitories specifically housing prisoners with HIV. A handful of prisoners had been allowed to live and work in non-segregated settings in work-release programs, Winter said.


Currently, the inmates with HIV live, eat and exercise apart from the general population, according to court documents filed by the ACLU. Male inmates in the HIV dormitories were given white armbands that signal their medical status.


“First, we are isolated … like we are contagious animals,” Dana Harley, another prisoner who was a plaintiff in the case, said in a letter included in the court file. “It is like punishment three times over.”


Approximately 270 inmates out of the 26,400 in the state prison system have tested positive for the virus and none have developed AIDS, according to Alabama Department of Corrections spokesman Brian Corbett, who did not respond to inquiries about the ruling.


The judge plans to rule separately on the medical criteria for work release for HIV prisoners, according to his ruling.


(Editing by David Adams and Andrew Hay)


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AuntMinnie.com’s Year in Review examines biggest radiology stories of 2012






Radiology news and education portal AuntMinnie.com today published its inaugural Year in Review special report, offering a look back at the 10 biggest developments in medical imaging in 2012.


Tucson, AZ (PRWEB) December 20, 2012






Radiology news and education portal AuntMinnie.com today published its inaugural Year in Review special report, offering a look back at the 10 biggest developments in medical imaging in 2012.


Year in Review offers radiology professionals an analysis of the news stories that shaped medical imaging this year. The topics span the gamut, from economic developments such as pressure on Medicare reimbursement to technical issues like the use of the third-generation iPad for mobile interpretation of medical images.


“Radiology has come under pressure in the last several years due to economic concerns, but our Year in Review special report demonstrates just how vibrant the specialty remains,” said Brian Casey, editor in chief of AuntMinnie.com. “New technologies came to the fore in 2012 that promise to improve patient care, such as CT radiation dose reduction tools, breast density measurement applications, and PET radiopharmaceuticals for predicting which individuals may develop Alzheimer’s disease.”


Year in Review can be accessed on the AuntMinnie.com website at http://www.auntminnie.com.


About AuntMinnie.com



AuntMinnie.com is the premier online radiology news, information, transaction, and education site for all individuals affiliated with the medical imaging market. Rich in timely, original content and customer-centered products and services, AuntMinnie.com is designed to enhance the professional lives of its members through interaction, participation, exchange, and commerce. AuntMinnie.com is owned by IMV, Ltd. Additional information on AuntMinnie.com is available at http://www.auntminnie.com.


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Family Meals Help Kids Eat More Fruit & Veggies






One or two family meals a week may help kids eat more fruits and vegetables, a new study suggests.


In the U.K. study, children whose families always ate meals together consumed 4.4 ounces (1.5 portions) more fruits and vegetables a day compared with children whose families never ate together.






And kids who had family meals just once or twice a week consumed 3.4 ounces (1.2 portions) more produce a day.


“Modern life often prevents the whole family from sitting round the dinner table, but this research shows that even just Sunday lunch round the table can help improve the diets of our families,” said study researcher Meaghan Christian, of the University of Leeds.


Family meals may provide an opportunity for children to learn healthy eating habits from their parents or siblings, and are also an incentive to plan meals, the researchers said.


Cutting fruits and vegetables into smaller pieces also appeared to increase consumption. Children ate half a portion more of fruits and vegetables (1.4 ounces) if their parents said they always cut up these foods.


The majority of children in the United States, Europe and Australia don’t consume the recommended daily amount of fruits and vegetables (five servings a day), the researchers said. [See 10 Ways to Promote Kids' Healthy Eating Habits].


Previous research has shown that children who dine with their families are less likely to be obese and more likely to eat healthy foods.


The new study’s findings are based on information from 2,000 elementary school children in London, with an average age of 8. Parents answered questions about their child’s food consumption over the last day, as well as how often the family ate meals together. Sixty-three percent of the kids did not eat the recommended five servings of fruits and vegetables a day.


Because the results are based on parents’ reports of their kids’ food intake, they may be subject to bias, the researchers noted. Parents may overreport the amount of fruits and vegetables their child eats because a healthy diet is socially desirable. But the parents of children in the study did watch a DVD to learn how to properly report their child’s food intake, the researchers said.


The study is published today (Dec. 19) in the Journal of Epidemiology & Community Health.


Pass it on:One or two family meals a week may increase a child’s fruit and vegetable intake.


Follow Rachael Rettner on Twitter @RachaelRettner, or MyHealthNewsDaily @MyHealth_MHND. We’re also on Facebook & Google+.


Copyright 2012 MyHealthNewsDaily, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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Amgen to plead guilty in criminal case: prosecutors






NEW YORK (Reuters) – Biotech company Amgen Inc is scheduled to plead guilty on Tuesday in a criminal case in federal court in Brooklyn, New York, prosecutors said.


A brief statement from the U.S. Attorney‘s office gave no details of the charges Amgen would plead guilty to.






Representatives of Amgen could not immediately be reached to comment on the subject matter of the expected plea.


Amgen in October 2011 said it had taken a $ 780 million charge to settle a probe into allegedly illegal sales and marketing practices. The investigation, relating to sales of its anemia drugs Aranesp and Epogen, had been conducted for several years by federal prosecutors in Brooklyn and Seattle.


Amgen said at the time that if settlement discussions were successful, the $ 780 million would resolve federal probes and related state Medicaid claims as well as other litigation. But the company did not disclose when and if it would plead guilty to criminal charges.


The biotechnology company disclosed in court papers filed in 2010 that it has been under investigation by the Brooklyn federal prosecutor since 2006 in connection with alleged violations of the False Claims Act and other federal statutes.


(Reporting by Ransdell Pierson and Jessica Dye; Editing by M.D. Golan)


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Boehner opens door to tax hikes, shifts U.S. fiscal cliff talks






WASHINGTON (Reuters) – U.S. House of Representatives Speaker John Boehner‘s offer to accept a tax rate increase for the wealthiest Americans knocks down a key Republican road block to a deal resolving the year-end “fiscal cliff.”


The question now boils down to what President Barack Obama offers in return. Such major questions, still unanswered so close to the end of the year suggest, however, that no spending and tax agreement is imminent.






A source familiar with the Obama-Boehner talks confirmed that Boehner proposed extending low tax rates for everyone who has less than $ 1 million in net annual income, meaning tax rates would rise on all above that line.


Under current law, the 35 percent top tax rate is scheduled to expire on January 1, and would automatically go to 39.6 percent. Boehner’s proposal would allow that rate to rise as scheduled at a threshold of $ 1 million – putting it back to where it was during the Clinton administration.


The White House has not accepted the proposal and the source could not confirm any additional talks were held on Sunday between Obama and Boehner.


With just over two weeks before the fiscal cliff’s $ 600 billion in automatic tax hikes and spending cuts are triggered, threatening a new recession, there is little time to craft a comprehensive deal that will satisfy both Democrats and Republicans.


Until the latest Republican offer, made on Friday, Boehner had insisted on extending all of the Bush era’s lower tax rates, resisting Obama’s demand to let the marginal rates rise on income above $ 250,000. A rising chorus of business executives also had urged Republicans to agree to this.


Some lawmakers and congressional aides had predicted that Republicans, once serious negotiations began, might try to raise the $ 250,000 threshold, say to $ 500,000 or $ 1 million. They also speculated that Republicans, if forced into a tax rate hike on the upper-income groups, might seek a smaller increase, say to around 37 percent.


Although the White House has not accepted Boehner’s gambit, it could push negotiations away from entrenched, ideological positions.


“Boehner has now accepted the premise of higher rates. So now we’re just arguing over details. I think it’s a significant step,” said Greg Valliere, chief political strategist at Potomac Research Group.


A framework deal spelling out tax revenue and spending cut targets to be finalized in the new year could be possible, Valliere said.


“Boehner’s offer to allow tax rates to go up for taxpayers earning over $ 1 million fundamentally transforms fiscal cliff negotiations,” added Sean West, U.S. policy analyst at Eurasia Group, a political risk consultancy.


In a note to clients, West wrote that it signals, significantly, that Boehner ultimately believes a deal to avoid the cliff is still possible.


“The political burden is now shifted back to the president, who must be willing to take on his party in order to get a deal Boehner can ultimately pass. We do not think the president will overreach: Obama will work with Boehner to get to a deal.”


There are still several critical elements to a deal besides a tax rate increase on the wealthy, including Republican demands to cut spending on social programs.


Changes to the expensive Medicare and Medicaid health care programs for the elderly and the poor could be central to any deal, which must also include an increase in the federal debt limit needed by the end of February.


DEMANDS SOCIAL PROGRAM CUTS


Boehner conditioned his tax rate increase offer on Obama’s agreement to cuts in social program spending, often called entitlements.


Many Republican lawmakers want to raise the eligibility age for Medicare to 67 from 65. They also want to link Medicare to the income of recipients, making wealthier retirees pay more for their care.


Currently, Medicare does have some means testing, charging higher premiums for coverage of doctors visits and prescription drugs to individuals earning more than $ 85,000 and married couples earning more than $ 170,000. Only about 5 percent of recipients pay these higher premiums.


Thus far, Obama has offered only about $ 400 billion in 10-year entitlement savings, mostly through small adjustments in reining in health care costs – not fundamental changes such as raising the eligibility age.


And just as Boehner faces opposition in his own party to raising any tax rates, Obama faces opposition to cuts to Medicare, Medicaid and Social Security from Democrats, who pledged in election campaigns they would protect these programs.


A major bloc of congressional Democrats has already signaled they will not accept major cutbacks in Medicare as part of any fiscal cliff deal.


House Minority Leader Nancy Pelosi of California and Maryland Representative Chris Van Hollen of Maryland are among the high ranking Democrats in the House who have come out forcefully in recent days against raising the age for eligibility for Medicare to 67 years of age.


“Given the level of savings that is being talked about from Medicare, you can’t get it all from providers and drug makers,” said Paul Heldman, an analyst at Potomac Research, which tracks Washington policy for investors.


“So opponents of raising the eligibility age have reason to believe beneficiaries will take some sort of hit if a mega-deal is cut,” he said.


If Republicans are not successful in securing entitlement program cuts in exchange for a tax-rate increase on the wealthy, they are adamant about using a debt-limit increase as leverage to overhaul Social Security and Medicare.


The U.S. Treasury expects to reach its $ 16.4 trillion statutory debt cap by year-end, and will exhaust its remaining borrowing capacity around mid-February, risking a potential default.


Louisiana Republican Representative John Fleming, a member of the conservative Tea Party caucus who has never voted to increase the debt ceiling, said he would support a debt limit hike if it were part of a deal to make Medicare and Social Security sustainable.


The pace of activity could pick up the coming week.


House Republicans were told to prepare for a possible weekend session next week, potentially interrupting travel plans for the long Christmas holiday weekend.


House Majority Leader Eric Cantor scheduled “possible legislation related to expiring provisions of law,” a reference to the expiring tax cuts, for the end of the week, portending a weekend session. Cantor has said the House would meet through the Christmas holidays and beyond.


(This story was fixed to correct current top tax rate to 35 percent from 36 percent)


(Additional reporting by Thomas Ferraro, Richard Cowan and Kim Dixon; Editing by Fred Barbash, Todd Eastham and Jackie Frank)


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Health workers march in Spain’s capital against cuts, reforms






MADRID (Reuters) – Thousands of health workers, on strike since last month, marched on Sunday in Madrid to protest against budget cuts and plans from the Spanish capital’s regional government to privatize the management of public hospitals and medical centers.


It was the third time doctors, nurses and health workers have rallied since the local authorities put forward a plan in October to place six hospitals and dozens of medical practices under private management. The plan also calls for patients to be charged a fee of 1 euro for prescriptions.






Workers launched an indefinite strike last month against the plan, which has not been endorsed by the centre-right government of Prime Minister Mariano Rajoy. Health workers in the capital are striking Monday-Thursday each week and seeing patients only on Fridays, while also responding to emergencies.


Spain’s 17 autonomous regions control health and education policies and spending. They have all had to implement steep cuts this year as the country struggles to meet tough European Union-agreed deficit targets.


Dressed in white scrubs, the protesters shouted slogans such as “Health is not for sale” and “Health 100 percent public, no to privatizations”.


“Of course, privatization can be reversed. Actually the question is not if it can be reversed, because privatization should never have a future,” said Luis Alvarez, an unemployed man from Madrid attending the demonstration.


Belen Padilla, a doctor at Madrid’s hospital Gregorio Maranon, said one million citizens had already signed a petition rejecting the plan.


(Reporting by Reuters Television; Writing by Julien Toyer; Editing by Peter Graff)


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Booze, smokes on agenda for quirky gov’t group












BELTSVILLE, Md. (AP) — Deep in a secure laboratory just outside Washington sits the federal government‘s heaviest smoker.


It is a half-ton hulk of a machine, all brushed aluminum and gasping smoke holes, like a retrofit of equipment used on an Industrial Revolution production line. It can smoke 20 cigarettes at once and conclude which are unsafe because they are counterfeit and which are unsafe merely because they are cigarettes.












Down the hall, a chemist tests shiny flecks from a bottle of Goldschlager, the spicy cinnamon schnapps, to make sure they’re real gold. A government agent was sent out to stores to buy it and hundreds of other alcoholic drinks randomly chosen for analysis.


Back at headquarters in downtown Washington, a staffer prepares for a meeting of the Tequila Working Group — a committee created to mollify Mexico and keep bulk tequila flowing north across the border.


These are the proud scientists, rule-makers and trade ambassadors of the Alcohol and Tobacco Tax and Trade Bureau, one of the federal government’s least-known and most peculiar corners.


The bureau, known as TTB, collects taxes on booze and smokes and tells the companies that produce them how to do business — from approving beer can labels to deciding how much air a gin bottle can contain between lid and liquor.


It decides which valleys in Oregon and California can slap their names on wine labels, what grapes can go into wine and which new alcoholic drinks are safe to import.


The bureau is one example of the specialized government offices threatened by Washington’s current zeal for cost-cutting. Obama administration officials weighed eliminating it during the fiscal stalemate of 2011, according to news reports at the time. Its officials were called to the White House budget office to justify their existence — or risk having their duties split between the Internal Revenue Service and the Food and Drug Administration.


The White House ultimately left the bureau’s $ 100 million budget in place for this year — perhaps because it spends far less money to collect each tax dollar than its counterpart, the IRS. But officials there remain hyper-aware of their vulnerability as Republicans and Democrats look to squeeze savings from unlikely places.


If they look closely, the belt-tighteners will discover an agency whose responsibilities often appear to conflict — a regulator that protects its industry from rules it deems unfair, a tax collector that sometimes cuts its companies a break.


Some of its decisions are open to negotiation. A tequila-like liquor with a scorpion floating in it made scientists balk until the producer convinced them that the scorpions are farm-raised and non-toxic.


In other words, this may be the only federal agency that responds favorably to receiving scorpion candy in the mail — an edible tool for persuading scientists that the arthropods were fit for human consumption.


If labs, rules and taxes weren’t enough for the bureau’s 500-odd employees, they also have law enforcement authority. TTB investigators can send people to jail for things like removing alcohol from the production line and reselling it before it has been taxed by authorities.


With all these responsibilities, it’s no surprise the agency’s priorities sometimes clash. The bureau gives companies a wide berth on some rules and taxes, officials and experts say, mainly because of its small size and history of collaborating with business. It has granted millions in tax givebacks because of concerns that companies will sue and tie up government resources.


“Because we’re regulated by such a friendly agency, and because enforcement isn’t huge, there’s a level of non-compliance that’s sort of acceptable,” says Rachel Dumas Rey, president of Compli, a California company that helps wineries comply with Treasury policy.


Agency officials say they use scant resources where they can make the most difference, generally on the biggest producers or companies where there is an indication of wrongdoing.


Yet last July, the bureau slashed a tax bill for the multinational agribusiness conglomerate Cargill from $ 839,370 to $ 63,000. Cargill failed to report or pay taxes on about 23,000 gallons of nearly pure industrial alcohol that leaked from a rail car, violating several U.S. laws, according to documents on the bureau’s website.


Since 2010, under similar deals with alcohol and tobacco companies, the agency has forgiven more than $ 25.4 million; the total amount is unclear because some public documents do not list the size of the tax bill or penalty that is being reduced. Nine companies persuaded the agency to slash their bills by more than 95 percent, including Procter & Gamble’s Olay subsidiary, which uses alcohol in its skin care products.


Tom Hogue, a spokesman for the bureau and former explosives inspector, says it only agrees to reduce companies’ tax bills “if we are satisfied that the (remaining) penalty is commensurate with the violation and is sufficient to deter future illegal conduct.” In cases where settlements are granted, Hogue says, “they allow us to use our resources to counter non-compliance, instead of tying them up in court.”


When the alcohol and tobacco bureau was split from the Bureau of Alcohol, Tobacco and Firearms, it held on to the former agency’s tax collection duties, including for firearms and ammunition. It’s still the government’s third-biggest revenue collector, after the IRS and Customs and Border Protection. It took in $ 23.5 billion in federal taxes on alcohol, tobacco, weapons and ammo in the fiscal year ended Sept. 30, 2011, the most recent data available. That amounts to $ 468 for every dollar the agency spent collecting taxes — more than twice the IRS’ ratio, officials note.


The bureau also works with government trade officials to protect and expand international markets for American alcohol and tobacco. Its expertise is crucial in negotiating with Europeans about wine labeling, or standing up to countries that refuse to recognize American “straight bourbon” for what the government says it is: corn whiskey stored in charred new oak containers for at least two years.


In this role, the agency has come to the rescue over the years of whiskey lovers in China, Colombia and Brazil. Those countries’ governments tried to ban booze containing too much fusel alcohol, the pungent byproduct of fermentation that gives some whiskey its spicy, solvent-like aroma. Working through international trade groups, armed with data from TTB scientists, U.S. officials spent years convincing them to reverse their policies and allow the importation of whiskey that meets American standards. That was a win for American alcohol producers.


Sometimes, to protect U.S. producers, the bureau erects trade barriers of its own. Under a proposal by the bureau last spring, anything labeled Pisco must have originated in Chile and Peru. (Pisco is a South American grape brandy whose signature cocktail, the Pisco Sour, is so celebrated that it has its own official Peruvian holiday.)


Aspiring Pisco producers in Bolivia, in the U.S. government’s eyes, can take a hike.


This is no accident: It’s the result of a trade agreement that compels Chile and Peru, in exchange for the Pisco rule, to make sure any bourbon sold there is from the U.S. and meets this country’s standards.



The U.S. is the only nation with an alcohol regulator based in its Treasury Department. Treasury was the federal government’s monitor of products seen as sinful or illicit even before Prohibition began in 1919.


When the government first tried to crack down on cocaine and heroin in 1914, it did so by enacting steep taxes. For a time, marijuana also was controlled by imposing taxes so high, it was hoped, that people might lose interest.


After Prohibition was repealed in 1933, the government tried to keep a handle on the alcohol industry by writing production standards for alcohol directly into the tax code. That’s where wine’s alcohol content is limited to 24 percent.


The government uses taxes to control social phenomena, explains Bill Foster, who ran the bureau’s headquarters before retiring this summer.


“Tobacco and alcohol are two of those commodities,” Foster says.


The taxes are collected directly from producers and manufacturers, which pass those costs along to consumers. Liquor producers generally pay a flat rate of $ 13.50 per proof gallon — a gallon of liquid that is one-half alcohol by volume. Small cigars and cigarettes are taxed at a rate of $ 50.33 per 1,000 sticks.



The current Alcohol Tobacco Tax and Trade Bureau was split from the Bureau of Alcohol, Tobacco and Firearms in 2003. ATF was moved to the Justice Department, where it focuses on firearms, explosives and violent crime.


Officials who regulate and tax alcohol and tobacco remained at Treasury, where they continue to ensure that wine doesn’t contain pesticides and absinthe is free of thujone, the psychoactive ingredient — now banned — that gave it its hallucinogenic reputation.


That’s how Dr. Abdul Mabud found himself overseeing 26 chemists at a lab in Beltsville, Md., that tests hundreds of bottles, cigarettes and perfumes every year.


One afternoon, Mabud holds aloft a jar of pure, clear alcohol containing a coiled king cobra, its hood flared and forked tongue extended. Surrounding it are smaller green snakes that appear to be biting each other’s tails.


The snake liquor was submitted for consideration as an import from east Asia, where snakes are believed to increase virility.


“With that much snake in there, it’s probably not a beverage,” Mabud says, explaining why the shelves of America’s liquor stores and supermarkets are free of giant, gin-soaked snakes.


Mabud traces his lab’s history to 1886, when Congress passed steep taxes on margarine — at the time, an upstart competitor to the nation’s dairy products. The 1886 law aimed to prevent crooked margarine-pushers from selling their product as butter. Treasury’s first food-quality lab was set up to preserve butter’s integrity.


Today, the bureau owns some of the most sophisticated equipment available, including the smoking machine, which can be set to inhale in at least three ways, depending on how long and hard the smoker being simulated prefers to puff: light, medium and Canadian. The last one is when the perforations around the cigarette’s filter are blocked and the machine takes bigger, more frequent puffs. It was invented by the Canadian government, and does not necessarily reflect the actual smoking habits of Canadians, says Dawit Bezabeh, chief of the bureau’s tobacco lab.


“That’s the worst-case scenario,” he says.



Officials are less chatty about a third agency priority: The diplomatically sensitive work of promoting the international alcohol and tobacco trade.


The bureau helps strike deals with other countries that have liquor industries, like the one with Peru and Chile over Pisco. The idea is to protect U.S. alcohol and tobacco producers from unfair competition. Jim Beam’s prices might be easily undercut, for example, if an overseas firm was allowed to label something as bourbon even though it was aged in a cask that is neither charred nor oak nor new.


That’s how the Tequila Working Group was born. Citing safety concerns, Mexico had threatened to stop exporting bulk tequila — a commodity that supports 500 U.S. bottling jobs. After the bureau agreed in 2006 to regular meetings with Mexico’s tequila industry, Mexico backed down. The jobs were saved.


Until the early 2000s, the U.S. negotiated wine-making standards as part of a European wine trade group. As the American wine industry blossomed, officials began to believe that the group was favoring European wineries, for example, by refusing to endorse American agricultural methods. Every member of the group had veto power, and France was willing to use it.


The U.S. escaped Europe’s dominance by joining with other oenological up-and-comers like Australia, Argentina, Canada, Chile, New Zealand and South Africa to form the World Wine Trade Group. The group encourages countries to accept each other’s wine-making methods.



Its complicated history helps explain why the bureau looks and acts different from most government offices. As a tax-collecting agency, it wants to see its industries thrive. As a consumer-protection outfit tasked with keeping antifreeze-spiked wine off the market, the bureau must rein in dangerous, sloppy practices by industry members.


If other government agencies ran that way, the Consumer Product Safety Commission would be promoting U.S. baby crib makers at the same time it evaluated their products as potential death traps.


“There’s some peril with that kind of approach,” says Jeff Bumgarner, a professor of criminal justice at the University of Minnesota who studies the history of federal law enforcement. “The trade part of your mission is one of support and standing up the industries, and the tax collection part and the regulatory part and the compliance part is one of holding those industries in check.”


That basic conflict leaves the U.S. government with an alcohol regulator that recently hosted industry executives at conferences to educate them about the bureau’s rules and encourage “voluntary compliance,” then months later raided a Native American reservation that was suspected of harboring cigarette tax evaders.


Critics say the bureau’s close relationship with industry makes it less likely to take a hard line against violators.


Foster sees it another way. He says agents and officials like him are more effective overseers of the industry because they started out working on the distillery floor, measuring batches of liquor and handing producers their tax bills.


“It gave us all a significant understanding of how the industry operates and what their challenges were,” he says.


Agency officials say they are making the most of limited resources, and doing better than most federal departments. And their workload is increasing steadily. The alcohol and tobacco bureau is responsible, for example, for approving every label to be used on an alcohol product in the U.S. As the number of microbrewers and microdistilleries explodes, the work of reviewing those labels is becoming a heavier lift.


The bureau now regulates more than 56,000 companies, an increase of 27 percent since 2007. In that time, its core budget rose only 8 percent.



Like any government office, the agency has had its share of hiccups. Agawam grapes were known on U.S. wine labels as Agwam grapes until the bureau corrected its spelling error in rules published last year.


Vintners with leftover Agwam labels were given until October to stop using them.


___


Daniel Wagner can be reached at www.twitter.com/wagnerreports.


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Amarin raises funding for heart drug, partnership worries pull down shares












(Reuters) – Biopharmaceutical company Amarin Corp Plc said it raised $ 100 million in non-equity financing that will help it form a sales force to launch its heart drug Vascepa, but disappointed investors hoping for a sale or partnership.


Amarin shares fell 22 percent in extended trade, after closing at $ 11.95 on the Nasdaq on Thursday.












“(Strategic) discussions are still quite active but at some point we’ve got to move forward,” CEO Joseph Zakrzewski said on a conference call with analysts.


Israel’s Calcalist financial daily said in November that the world’s largest generic drugmaker Teva Pharmaceutical Industries and British drugmaker AstraZeneca were both looking to buy the company.


The U.S. Food and Drug Administration in July approved Vascepa capsules alongside diet to reduce triglyceride levels — a blood fat that contributes to heart disease — in adult patients with severe hypertriglyceridemia.


Amarin said Thursday it will hire 250 to 300 sales professionals to launch Vascepa in the first quarter of 2013.


The decision to hire a sales force implied that Amarin is ready to go it alone, analyst Jon LeCroy of MKM Partners said, adding that this is being viewed negatively by investors.


“With the backing of a major pharmaceutical company, there will be sales reps available as well as more dollars to market the product. So the assumption would be that it could be a much bigger product if a bigger company sells it,” LeCroy said.


WAITING ON EXCLUSIVITY


Amarin had earlier indicated that the FDA decision on Vascepa’s marketing exclusivity would have an impact on whether the company gets acquired, forms a partnership on the drug, or sells the heart pill on its own.


Amarin is awaiting a decision from the regulator regarding a new chemical entity (NCE) status for Vascepa, which will grant the company marketing exclusivity for five years. The pill is also patent protected until 2030.


LeCroy said with an NCE most major pharmaceutical companies would be interested in Amarin, given that the status guarantees some minimum exclusivity compared with patents that can be challenged.


The company is planning to price Vascepa on par with GlazoSmithKline’s competing Lovaza, CEO Zakrzewski said on the call.


He added that reimbursement for the drug will be available to most managed care clients by the time of its launch.


The financing deal for the hybrid debt-like instrument was made with an investment fund managed by Pharmakon Advisors.


(Reporting By Vrinda Manocha and Balaji Sridharan in Bangalore; Editing by Don Sebastian and Anthony Kurian)


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U.S. House Democrats introduce new meningitis legislation












WASHINGTON (Reuters) – Two Democratic lawmakers in the U.S. House of Representatives introduced legislation on Wednesday aimed at bolstering federal oversight of compounded drugs like the tainted steroid injections blamed for a deadly fungal meningitis outbreak.


But the legislation is not likely to move forward in the Republican-controlled chamber. In fact, aides from both parties said neither the House nor the Democratic-led Senate is expected to vote on meningitis legislation this year, given the little time remaining and the overarching focus on so-called “fiscal cliff” deficit-reduction talks.












Some Democratic lawmakers have warned that enacting tighter federal standards for compounded drugs could become more difficult in the new year, as the meningitis outbreak wanes and loses public attention.


The outbreak, linked to steroid injections from the Massachusetts-based New England Compounding Center, has sickened 541 people, 36 of whom have died, according to the U.S. Centers for Disease Control and Prevention.


The public health disaster has also spawned several investigations including a U.S. grand jury probe.


Drug compounding is a traditional pharmacy practice in which pharmacists alter or recombine drugs to meet the special needs of individual patients with a physician’s prescription. The practice is regulated mainly by state pharmacy boards that do not impose the stringent safety and efficacy standards that the Food and Drug Administration requires of drug manufacturers.


But in the past few decades, some compounding pharmacies, such as NECC, have become large operations selling thousands of drug doses to clinics, hospitals and other healthcare providers across state lines.


Critics say those operations rival drug manufacturers in scale and should be subjected to strict FDA standards. But past attempts to strengthen federal regulation has been defeated by industry lobbying and legal maneuvering.


FDA has lately come under fire in Congress, mainly from Republican lawmakers who say it has the authority to act against problem compounders but failed to take effective action against NECC despite problems dating back ten years.


Public Citizen, an advocacy group that tracks drug safety issues, has called for an investigation of FDA’s failures and urged the agency to inspect other compounders where problems have also surfaced over the past several years.


The legislation introduced on Wednesday by Democratic representatives Rosa DeLauro of Connecticut and Nita Lowery of New York is the second House Democratic measure to emerge since the outbreak first surfaced in mid-September.


The bill, known as the SAFE Compounding Drugs Act, would require compounding companies to register with the FDA, allow the agency to set minimum production standards and impose new labeling restrictions on compounded drugs.


Representative Ed Markey, a Democrat from Massachusetts, also introduced a measure to address FDA’s authority last month.


The agency itself has called on Congress to allow it to set national standards for large drug compounding operations. FDA officials are scheduled to discuss a potential new regulatory structure during a meeting with state officials on December 19.


(Reporting by David Morgan; Editing by Jilian Mincer and Tim Dobbyn)


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HIV Epidemic in Latin America, Caribbean: Making Progress












Right before World AIDS Day 2012, a colorful exhibit was launched at the Pan American Health Organization‘s headquarters in Washington, D.C.


Argentine artist Fabian Rios Rubino‘s United Colors of HIV, previously on display at the Embassy of Argentina, is a colorful acrylic mix, a veritable rainbow.












It was inspired by a controversial 1991 United Colors of Benetton ad campaign showing AIDS activist David Kirby on his deathbed, surrounded by family.


RELATED: HIV Vaccine Under Study May Last A Lifetime


The bright colors of Rubino’s work are meant to point out a new day, a new view and continued progress against HIV and AIDS—and how far some parts of the world have come since 1991.


It was the perfect backdrop for the PAHO statistical update on HIV and AIDS in Latin America and the Caribbean, released to coincide with World AIDS Day.


The face of HIV/AIDS in Latin America and the Caribbean is changing, thanks to widespread access to anti-retroviral drugs as well as prevention education, according to PAHO.


Between 2005 and 2011, the number of AIDS deaths dropped by 20 percent in Latin America and the Caribbean.


In some countries, the decline is even higher, according to the UNAIDS World AIDS Day Report. For instance, deaths in the Dominican Republican dropped 61 percent from 2005 to 2011.


There’s more good news: Both Latin America and the Caribbean now have the highest level of anti-retroviral treatment coverage of any mid- to low-income region in the world, PAHO officials say.


In Latin America, about 68 percent of people who need treatment now get it.


In the Caribbean, it’s 67 percent.


Globally, 8 million of the 14.8 million people eligible for HIV treatment are on it, according to the UNAIDS World AIDS Day Report 2012.


Mother-to-infant transmission of HIV is down, too, by 32 percent in the Caribbean since 2001 and by 24 percent in Latin America.


REALTED: Awareness of HIV Risk Has Dropped Among Gay Men Even As Infection Rates Rise


The advances are due to an all-encompassing approach, according to Dr. Gina Tambini, PAHO area manager for family and community health.


“These new developments reinforce the importance of an integrated approach toward HIV prevention, treatment and care, and alignment with programs and services for maternal and child health, sexual and reproductive health, adolescent health, and others,” she says in a statement.


Within the Americas epidemic, each country faces a unique situation, according to an overview of HIV and AIDS in Latin America produced by Avert, a U.K.-based AIDS and HIV charity.


For instance, the  ”machismo” culture can make some Latin America countries downplay the extent of their HIV infections among men having sex with men, sometimes not targeting them in prevention efforts.


Yet, in other countries—Mexico and Peru are given as examples—high-profile residents have acknowledged their orientation and that the epidemic there is driven at least partially by men having sex with men.


Poverty, a shortage of resources, and dependence on non-governmental funding to stop and prevent HIV/AIDS have slowed progress, Avert says.


In 2011, according to the UNAIDS 2012 Global Report, 1.7 million died of AIDS-related causes globally. Another 2.5 million became newly infected. In all, 34 million are infected, but half do not know their status.


Despite those challenges, PAHO officials contend that progress will continue. The name of the World AIDS Day 2012 theme—Getting to Zero—says it all.


That goal includes no new infections, no deaths and no discrimination.



Kathleen Doheny is a Los Angeles journalist who writes about health. She doesn’t believe in miracle cures, but continues to hope someone will discover a way for joggers to maintain their pace.


Medications/Drugs News Headlines – Yahoo! News


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Geron drops brain cancer drug, to cut jobs












(Reuters) – Geron Corp confirmed it will discontinue development of an experimental drug to treat cancer that has spread to the brain from elsewhere in the body and also cut about 40 percent of its workforce, after patients failed to respond to the drug in a mid-stage study.


The company said it will now focus on the development of another drug candidate, imetelstat, as a treatment for blood cancers and some types of solid tumors.












The brain cancer drug, GRN1005 and imetelstat’s development in blood cancers were the only hopes that Geron‘s shareholders had after the company warned investors in September that it would stop developing imetelstat as a breast cancer treatment.


Geron now has only imetelstat in its pipeline, after dropping its brain cancer drug and exiting stem-cell research in November 2011.


The company signed a deal last month to sell its stem-cell assets to BioTime Inc.


On Monday, Geron also said Chief Financial Officer Graham Cooper will be leaving to pursue other opportunities. Treasurer and Chief Accounting Officer Olivia Bloom will replace Cooper.


Menlo Park, California-based Geron shares, which had closed at $ 1.48 on Monday on Nasdaq, fell 16 percent to $ 1.24 in extended trading.


(Reporting by Vidya P L Nathan; Editing by Joyjeet Das)


Diseases/Conditions News Headlines – Yahoo! News


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